This observational study aims to compare the efficacy and safety of intrathecal morphine versus epidural analgesia in postoperative recovery following radical cholecystectomy. Methods: 40 patients posted for radical cholecystectomy were divided into two groups of 20 patients each, epidural analgesia group (EDA) and intrathecal morphine group (ITM). The EDA group received continuous epidural infusion of 0.2% Ropivicaine with inj. Fentanyl 2 mcg/ml at 5-6 ml/hr in the postoperative period while the ITM group received 150-200 mcg of morphine intrathecally before general anaesthesia was administered. VAS will be assessed for 72 hours postoperatively, rescue analgesic consumption in the first 24 hours as well as total analgesic consumption in the next 48 hours will be recorded, time for first rescue analgesic use, time for ambulation, duration of stay inICU, total duration of stay in hospital will be assessed. Side effects if any will be recorded.