The study aimed to Effect of COVID-19 infection on levels Haptoglobin and Beta trace protein and some of Biochemical parameters COVID19. The study groups included 30 patient men infected with COVID-19, 30 men who recovered and 30 healthy men as a control group. Protein and biochemical assays include: Beta trace protein , Haptoglobin , LDH, AST , Na, Albumin , ferritin , Albumin / creatinine ratio (ACR)