Acute pancreatitis is an inflammatory disease of the pancreas and can be caused by several factors such as gallstones, alcohol, trauma, infections, and hereditary factors. The incidence of alcoholic pancreatitis is higher in male; however, more women develop this disorder since gallstones occur with increased frequency in women. Gallstones are the most common cause of acute pancreatitis worldwide. The aim of the study is to find out early indicators of Acute Biliary Pancreatitis. This retrospective study was conducted for a period of 2 years on 650 patients of all age groups. The gallstone is the most common cause of AP. The female to male ratio in this study was 1.8:1. The mean age of male patients was 40.3+11.82 years and that of females was 39.6+9.65 years. Serum bilirubin, ALT and amylase when compared with biliary and non-biliary patients, the difference was found to be statistically significant. The difference between severity and type of pancreatitis was observed to be statistically significant with p < 0.05. The biliary pancreatitis had statistically significant %age of SAP (23%) as compared to non-biliary pancreatitis (13.8%). The Severe Acute Pancreatitis (75%) had statistically significant >1-week hospital stays as compared to moderately SAP (46.9%), followed by mild AP (5.4%). The present study found that there is a significant co-relation between young age, female gender, raised serum bilirubin, ALT & Amylase and these factors are predictors of Acute Biliary Pancreatitis.