Objective: The present study was conducted to assess the dyslipidemic status in periodontitis with or without type 2 diabetes. Materials and Methods: This study is designed as hospital based cross sectional study.100 chronic periodontitis participants were included in this study. 50 were systemically healthy and 50 participants were type 2 diabetics. Demographic variables, clinical parameters of periodontal health, glycemic control and serum lipid profile were assessed. Statistical expressions were made using Students T test and Chi square test. Results: Dyslipidemia is evident in chronic periodontitis with Type2 diabetes and subjects with chronic periodontitis also showed aberrant serum lipid profile. Conclusion: Dyslipidemia is the key risk factor for cardiovascular diseases .It is apparent that both chronic periodontitis and type2 diabetes predispose individuals to cardiovascular disease by exerting their influence in serum lipid profile.