Abstract Introduction: Determining the prevalence of common psychological problems—Anxiety, Somatic symptom disorder and Depression—in general practice population, investigating their association with psycho-social stressors and determining the diagnostic overlap of above mentioned three disorders are the main aims of this study. Methods: In this cross-sectional study, 132 patients were approached, out of which 100 patients agreed to participate in this study and later on responded to the questionnaire (75.7%). Anxiety of the sample was assessed with the help of GAD-7 (Generalised Anxiety Disorder 7) whereas assessment of depression was done with Patients Health Questionnaire-8 (PHQ- 8). Patients Health Questionnaire-15 (PHQ-15) was the scale which was used for somatic symptom disorder. Results: Of the approached 132 patients, 100 responded to the 12-item General Health Questionnaire (GHQ), with a response rate of 75.7%. Out of these 100 subjects, 63 were males and remaining 37 were females. 12-item General Health Questionnaire (GHQ- 12) was administered to all the patients and 47 out of these 100 patients were identified as probable cases (47%). 44% males (28 out of 63) and 51% females (19 out of 37) were found out to be GHQ positive cases, indicating that they have some psychological problem. Prevalence of anxiety, somatic symptom disorder and depression from the studied sample was 42%, 28% and 22% respectively. Males had more depression (27%) than females (13.5%) in the study. Women were more likely to present with anxiety (46% versus 36.5%) and somatic symptom disorder (35% versus 23.8%) compared to men. Overlapping of these three common psychological problems was the major outcome of this study. Overlapping of anxiety with depression is 17% and anxiety with SSD is 31%. Overlapping of all the three variables is 21%. Only 0.4 % overlapping is found in depression and SSD, indicating anxiety is more commonly associated with Somatic symptom disorder than depression. Conclusion: Somatic symptom disorder and depression was similar in term of their prevalence, but anxiety was noticed to be at higher level in patients at general practice. Anxiety, somatic symptom disorder and depression in the study sample had high degree of coexistence also. 1. INTRODUCTIO