Abstract: Objective: Optimization of diagnostics and treatment of gastroschisis in newborn infants. Material and Methods: We observed 92 patients with gastroschisis. Among them boys - 51 (55,4%), girls - 41 (44,6%). Born full-term - 47 (51%), preterm - 45 (49%) children. On the first day (0-24 hours) after birth received 78 (84.8%) patients, 24-48 hours - 12 (13%) and 48-72 hours - 2 (2.2%) children. Results: In 60 (65.3%) revealed a total form, in 27 (29.3%) and subtotal in 5 (5.4%) - a local form of gastroschisis. 51 (55.4%) of 92 children diagnosed prenatally pathology. Ultrasonographic findings of gastroschisis were uneven contours of the anterior abdominal wall, and the defect was located a short distance from the umbilical cord. In our studies, ultrasound accuracy in gastroschisis was 100%. Surgery performed 84 (91,3%) patients. 65 (77,4%) neonates with total, subtotal and local form performed radical surgery. In 17 (18.5%) cases made-stage surgical correction. Postoperatively, 52 died (61.9%) children. The most common cause of postoperative mortality were aspiration pneumonia, and sclerema oligoanuria as a result of hypothermia on the road and a painful shock and sepsis and necrotizing enterocolitis, cardiovascular and respiratory failure.