Online ISSN: 2515-8260

Determination of cardiovascular autonomic neuropathy in type II DM patients

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Amit Varshney1 , Vidya Sagar Ram2 , Kanhaiya Prasad3

Abstract

Background: The diabetic neuropathy, including the cardiovascular autonomic neuropathy (CAN), is a common complication of type 1 and 2 diabetes that leads to high mortality and morbidity. The present study was conducted to determine CAN in type II DM patients. Materials & Methods: 168 type II DM patients of both genders were recruited. Resting heart rate, blood pressure, and body mass index (BMI), systolic blood pressure (SBP) ≥140 mmHg or diastolic blood pressure (DBP) ≥90 mmHg, fasting lipid profile (low-density lipoprotein/LDL, high-density lipoprotein/HDL, triglycerides/TG) and cardiac autonomic function was evaluated with the CAN system analyzer as early, definite and advanced CAN. Results: CAN was seen in 66 patients. The mean age (years) was 45.2 and 44.5, duration of diabetes (years) was 6.1 and 12.3, SBP (mm Hg) was 130.4 and 134.5, DBP (mm Hg) was 86.2 and 87.6, resting heart rate (beats/min) was 76.3 and 87.4, LDL (mg/dl) was 102.4 and 98.6, HDL (mg/dl) was 40.5 and 38.1 and TG (mg/dl) was 165.2 and 184.6 in CAN- and CAN+ patients. The difference was non- significant (P> 0.05). Severity of CAN found to be early in 20%, definitive in 45% and advanced in 35%. The difference was significant (P< 0.05). Conclusion: Type II diabetes patients had high prevalence of cardiac autonomic neuropathy.

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