Abstract Nowadays people mainly abuse designer drugs, which are harmful to them. These drugs are prepared in clandestine laboratory and are sold in market. The person wilfully started taking these designer drugs due to any reason and then gets addicted to them, when they didn’t get the desired dose withdrawal symptoms start to appear which include shakiness, vomiting, muscle pain and etc. During initial stages when a person started taking drug he/she feel happy joy full but later on they get addicted towards that drug and after sometime they increase the dose as depends on drug tolerance. People without knowing the harmful effects of the drug they started taking because they only know that they will get desired effect when they will take that drug. The drug abuser doesn’t know how that drug will affect him/her in future. This paper will focus on various designer drugs, their effects and metabolism including their legal status.