Diplocyclos palmatus (L.) Jeffry. commony known as Shivlingi belongs to family Cucurbitaceae had been widely used for its reported biological activities in indigenous system of medicine. The present investigation was designed to develop herbal tablet containing ethanolic extract of leaves of Diplocyclos palmatus (L.) Jeffry. for the treatment of inflammation. The developed herbal tablet was evaluated as per IP. Hence, present investigation established pharmacological evidences to support the folklore claim that Diplocyclos palmatus (l.) Jeffry. is used as anti-inflammatory agent.