Adhesive dentistry has undergone great progress in the last decades. There have been changes in chemistry, mechanism, number of bottles, application technique, and clinical effectiveness. The first, second and third generations are classified under historical title while; etch&rinse, self-etch and multi-mode adhesives are classified under the title of current clinical practice procedures strategies. The preferred properties of adhesive systems are biocompatibility with dental tissues, improved bond strength to dental tissues, and better resistance to chewing stresses. In recent years, the success rate of restorative treatment of teeth that have suffered from caries or loss of supporting tissue has increased considerably due to the developments in dentin donding systems.