Abstract: The increasing cases of sexual assaults and rape worldwide have made it very challenging for the various nations to deal with it. We are witnessing a huge technological advancement all over the seas. But so far, we have not been able to find any proper solution to deal with these types of crimes. If we talk about India, one of the fastest growing crimes are rape and sexual crimes of women and children. Rape is prevalent in both rural as well as urban areas, and now the cases of sexual assaults are being increasing in the group of high class and literate people. One of the major reasons for that is the increasing drug and alcohol abuse, which have a direct relation with increasing cases of sexual assault cases in the nation. About 70% of the sexual assault cases in India are reported which is committed while the Accused, victim or both are under the intoxication of some kind of drug or alcohol. The use of one such drug called the ‘Date Rape Drugs’ is becoming very prevalent in India. These drugs are used for exploiting the victim for the drug facilitated sexual intercourse. The reason why these drugs are becoming very popular among such abusers is that, these drugs produces effects which makes the victim physically helpless by reducing their physical strength so that they become unable to refuse the situation. Also, one more reason is that, this drug also affects the mental capability of the victim, thus the victim can’t remember and recall the situation. It is very easy for the perpetrators to mix these drugs in food and drinks of the possible victims because these drugs don’t have any smell, taste or any color. Thus, the date rape drugs are the perfect tool for such perpetrators. So, in this paper we will be discussing about such types of Date rape drugs which are being used at an extensive level in India, there mechanism that how they affect a person and its consequences.