Background Brain damage is caused by chronic alcoholism. Rural India has few published data. The aim of this study is to examine changes in the brain of chronic alcoholics living in rural areas using computed tomography (CT). Methods An analysis of chronic alcoholic patients referred from addiction centers at our tertiary care hospital over the course of two years was conducted in this prospective crosssectional study. Students' t-test and chi-square test comparisons were performed on nonalcoholic controls who were aged and sex-matched. In order to calculate the correlation coefficient, Pearson's correlation coefficient was used. The study included patients and controls from 30 to 45 years of age and 46 to 60 years of age. In each case, a CT scan was performed without contrast and indices of brain damage were calculated from the CT scan.