Online ISSN: 2515-8260

COVID, pandemic, intensive care unit.

Main Article Content

Pradeep Kumar Gupta, 2Himanshu Agarwal, 3 Saurabh Singhal, 4Keerti Manocha

Abstract

Aim: To find the level of uric acid in patients of chronic liver disease and its correlation, if any, with etiology and other parameters. Materials and Method: This was a prospective study conducted on North Indian population admitted in Department of Medicine during the period of 2020 and 2021. A total number of 50 patients diagnosed with chronic liver disease were included in this study. A detailed history was elicited from the patients regarding their present complaints; associated symptoms; alcohol intake, smoking, previous history of hypertension, diabetes mellitus, arthritis, hypothyroidism, any cardiac illnesses and chronic drug intake. All patients underwent an ultrasonogram abdomen and estimation of serum uric acid levels. Waist circumference in males and females was measured. Glycemic and Body mass index were recorded. Serum uric acid level was sent for analysis on the day of admission and was followed up. Results: Out of 50 subjects, 38 (76%) were males and 12 (24%) were females. Mean ± SD uric acid (mg/dl) among the study subjects was 6.69±2.92. Normal uric acid (3.1-5) was revealed among 24% of the subjects while higher uric acid/hyperuricemia was reported among 38 (76%) subjects. Mean uric acid was 4.03, 5.17 and 8.94 among the subjects having CTP class A, B and C respectively. Pearson correlation analysis revealed significant positive correlation between uric acid and total bilirubin, SGOT, SGPT and CTP Score. Conclusion: Elevated serum uric acid level might be a risk factor for the incidence of chronic liver disease. Hyperuricemia may act as a surrogate marker for assessing the prognosis of CLD.

Article Details