Abstract: Correlation dependence of the parameters of N - terminal cerebral natriuretic (NT-ProBNP) peptide and echocardiographic parameters for the diagnosis of pulmonary hypertension in children with CHD. For the study, 81 children aged 1 to 34 months were examined. The first group of CHD children without pulmonary hypertension, the second group - 56 CHD children with pulmonary hypertension. The results of our study show a statistically significant relationship between NT-ProBNP levels and structural features and pancreatic function during the development of PH with CHD.