The correction of malpositioned teeth in the mixed-dentition is a challenging task. If not done correctly it can be detrimental to the developing dentition and increase the probability of a complex orthodontic treatment in future. Factors such as severity of the malocclusion, patient’s compliance, availability of bone and space, type of treatment appliance used may dictate the success of treatment. The 2 × 4 orthodontic appliance has shown to produce a positive effect with de-rotation of the rotated/ malpositioned teeth and bringing them into correct arch alignment. Use of this appliance also eliminates the detrimental effects to the developing dentition and enhances patient’s smile with confidence. The 2x4 appliance consists of four brackets bonded on permanent maxillary incisors; bands with buccal tubes cemented on permanent maxillary first molars and a continuous arch wire. It has advantages over conventional techniques such as it provides total control of anterior tooth position, does not require any adjustment, allows precise and rapid positioning of the teeth and is very well accepted by the patient. This article illustrates the use of 2 x 4 appliance for correcting malocclusion in maxillary anterior teeth during mixed dentition period. The results achieved were satisfactory in regard to the esthetic demands of the patient as well as parents