Background and Objectives: Dengue, Enteric Fever and Malaria still remain diseases of public health importance due to their endemicity. Individuals residing in endemic areas are at risk of contracting these infections either concurrently or an acute infection superimposed on chronic infection. Concurrent infection with two agents can result in an illness with overlapping symptoms. This study aims to identify these infections during the study period as they follow seasonal pattern and increasing the burden in India. Materials and Methods: A cross sectional study conducted among febrile patients attending tertiary care centre, Hyderabad, Telangana from September to November 2021. A total of 85 febrile patients were investigated for Dengue, Enteric fever and Malaria using Dengue ELISA, WIDAL test and Malaria ELISA respectively.