Abstract: Background: In order to promote healing by primary intention the positioning and suturing of surgical flap is the main objective. Aim: To compare ‘Simple interrupted’, ‘Vertical mattress ‘ and ‘ Figure of 8’ suturing techniques in intraoral closure of PMMC flap in oncological ablative defects in Oral Carcinoma. Material and Methods: 30 histopathologically proven patients of oral carcinomas allocated to 3 groups equally in non randomized order requiring PMMC flap for rehabilitation of post ablative defect. Group A consisted patients underwent PMMC flap closure with Vertical Mattress suturing technique, Group B consisted patients underwent PMMC flap closure with Simple Interrupted suturing technique and Group C patients underwent PMMC flap closure with Figure of 8 suturing technique. Gaping and wound dehiscence and marginal necrosis assessed at 1st week and 3rd week postoperatively. Result: Irrespective of the type of suturing technique used there will be no significant difference in the healing outcome will be observed. Conclusion: Simple interrupted suture was fastest to take. Vertical mattress suture was more time consuming and Figure of 8 was also time efficient. No statistically significant advantage could be drawn in terms of Gaping, Dehiscence and Marginal necrosis amongst the three techniques considered in our study.