Abstract: Objective: Inflammatory and infectious diseases of the throat, tonsils, and adenoids are the major causes of pediatric diseases and their health care costs. The aim of this study was to compare the frequency of hemorrhage requiring surgical intervention after adenotonsillectomy in two methods of hot dissection and cold dissection in children aged 3-10 years. Methods: This clinical trial study was performed on 120 children who underwent adenotonsillectomy in Zahedan. Children were divided into two groups of hot dissection tonsillectomy and cold dissection tonsillectomy. Data were collected using an information form and analyzed by SPSS software and t-test statistical analysis. Results: Amongst 120 children evaluated, 60 were girls and 60 were boys. The mean age of the hot dissection group was 6.0 ± 2.1 years and the mean age of the cold dissection group was 5.5 ± 1.7 years. The overall frequency of hemorrhage requiring intervention in the cold dissection group was 1.7% and in the hot dissection group was 6.7%, but the difference was not statistically significant. The frequency of early hemorrhage, late hemorrhage, duration of operation, and pain score 12 hours after surgery was not different between the two groups, but the pain score was significantly higher in the hot dissection group one week after surgery. Conclusion: The frequency of postoperative hemorrhage was not significantly different in the two groups, but the pain intensity in the first week after surgery in the cold dissection group was significantly lower than the hot dissection group.