Background : The LMA is an ingenious supraglottic airway device that is designed to provide and maintain a seal around the laryngeal inlet for spontaneous ventilation and allow controlled ventilation at modest levels of positive pressure. LMA has gained extensive popularity for airway management during surgery. Aim and Objective : To compare Sevoflurane and propofol for laryngeal mask airway insertion and pressor response in adults. Materials and Method : This is Prospective randomized study, conducted in Department of Anaesthesiology, Bhaskar Medical College, Moinabad, for duration of one year, included 60 patients admitted for vascular, reconstructive, gynaecological, and day care surgeries, randomly allocated into two groups of thirty each Group‘S’ for Sevoflurane and group ‘P’ for Propofol using an automated computer generated list, after following inclusion and exclusion criteria and approved by institutional ethical committee. Results : There were 25 male and 35 female in the study and there was no significant difference was observe in the age group between the group. In our study mean time taken from induction to successful laryngeal mask insertion was significantly shorter with propofol compared with sevoflurane. In our study mean time taken from induction to successful laryngeal mask insertion was significantly shorter with propofol compared with sevoflurane. With the sevoflurane group, the LMA insertion has taken 68.12±0.49 seconds while propofol has taken 54.76 ± 0.16 seconds. Jaw relaxation has taken a long time in the sevoflurane group with P<0.001, which is highly significant. Conclusion : There was Delayed jaw relaxation with sevoflurane when compared to propofol delayed LMA insertion, thus time taken to insert LMA was more in Group S compared to group P. Hemodynamically all the patients from group S were stable compare to propofol but quality of anaesthesia provided was superior in group P