Background: Urinary Tract Infection (UTI) is one of the most common cause of hospital admission in adult males. Zinc is the second most abundant mineral in the body involved in the cell growth, cell division and regulation of immune system activity. In studies, zinc administration has been effective in improving gastroenteritis in adults. However, rare studies have been conducted on this subject. The present study aimed to compare the serum zinc level between males with febrile Urinary Tract infection & healthy males as control.