Online ISSN: 2515-8260

Comparison of ramosetron with ondansetron for prevention of postoperative nausea and vomiting in patients undergoing lower abdominal surgery

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1Deepak Naik P, 2 Fathima Sherif, 3 Safna Shajahan, 4Kshama S Ramesh

Abstract

Background: The goal of PONV management is to reduce or eliminate PONV and discomfort with minimum side effects. 5-HT antagonists work by blocking one of the pathways that lead to vomiting. Ondansetron is the most commonly used drug for this purpose. Ramosetron has a higher affinity for the 5-HT3 receptor than the older 5-HT3 antagonists, with an optimal dose of 0.6 mg and maintains its effects over two days.

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