Abstract: Background: Grafting the maxilla having cleft in alveolus is a part of comprehensive sequential treatment of cleft patients so as to facilitate eruption of permanent canine, achieve continuity of maxilla for orthognathic corrections and supporting alar bases. Unhindered soft tissue healing is critical to preventing graft exposure and achieving graft uptake. Poliglecaprone 25(monofilament) suture is known to have low capillarity. Thus it can be of benefit in achieving the required healing of soft tissue over cleft maxilla after bone grafting. Aim: To Compare Poliglecaprone 25(monofilament) and Polyglactin 910(multifilament) suture material in terms of soft tissue healing of surgical wound after cleft alveolar bone grafting. Material and Methods: Patients of unilateral cleft alveolus will have to be randomly divided into two sections. Group A comprising of patients in whom closure will be done by Poliglecaprone 25 whereas Group B of patients in whom closure will be done by Polyglactin 910.Success of the choice of suture material will be evaluated in terms of soft tissue healing, suture slack and number of inflammatory cells on suture surface. Result: Results will be analyzed using Student’s paired t test. It is expected that the healing will be significantly better in Group A than Group B. Conclusion: Efficacy of Poliglecaprone 25 in terms of soft tissue healing after alveolar bone grafting can be validated through this study.