Background: Midazolam and propofol by virtue of their antiemetic effect were found individually to reduce the incidence of intraoperative nausea and vomiting. This study compares the effects of midazolam and propofol in decreasing the incidence of nausea and vomiting in pregnant women undergoing lower segment caesarean section (LSCS) under spinal anaesthesia. It also assesses maternal sedation, neonatal outcome and other side effects