Introduction-Several studies have shown that the addition of adjuvants can help to improve patient safety, increase patient satisfaction, and enhance clinical efficacy. Therefore, the present study was conducted to compare the effectivenessof clonidine and buprenorphine as an adjuvant to bupivacaine in patients undergoing lower limb or abdominal surgery at a teaching hospital catering to a rural and semiurban population in North India. Methodology-This Randomized Prospective Double-Blind Study includes 108 patients, randomized into three groups of 36 patients each, Control Group-A (received Bupivacaine alone 3.0 ml + normal saline 0.5 ml.) Buprenorphine Group-B (group was received, 3.0 ml of 0.5 % hyperbaric Bupivacaine + 60 mcg (0.2ml) Buprenorphine) Clonidine Group-C (was received 3.0 ml of 0.5% hyperbaric Bupivacaine + 60 mcg (0.4ml) Clonidine). Time of onset of Sensory block was observed by Pin-prick method, and time of onset of Motor Blockade was observed by Bromage scale. Post-operative pain wasaccessed by visual analogue scale as various follow-ups. Results-The demographical profile of the patients were comparable in all groups. The mean VAS score was significantly lower in Group-C. The mean Bromagescore, onset of sensory and motor block was significantly lower in Group-C. However, the duration of sensory and motor block, as well as meantime of a sensory regression to LI, were significantly delayed in Group-C. Complications were also showed non-significant differences.