Online ISSN: 2515-8260

COMPARATIVE STUDY OF EFFICACY OF LABETALOL AND DEXMEDETOMIDINE FOR ATTENUATION OF HEMODYNAMIC STRESS RESPONSE TO LARYNGOSCOPY AND ENDOTRACHEAL INTUBATION: RANDOMIZED CONTROLLED STUDY

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Dr.Nisarg V. Patel1Dr. Nikita P. Mevada2Dr.Hina N. Gadani3*Dr.Shobhana Gupta4

Abstract

Tracheal intubation using a laryngoscope is considered to be the gold standard of airway management during administration of general anesthesia because of its several advantages including delivery of anesthetic gases and oxygen via positive pressure ventilation without inflationof stomach, minimal risk ofaspiration, access to tracheobronchial tree for pulmonary hygiene and drug administration (e.g., inhaledbronchodilators), improved surgical access to head andneck.1,2 Direct laryngoscopy and tracheal intubation during general anesthesia leads to sympathetic stimulation and release of plasma catecholamines concentration which manifests clinically as tachycardia, hypertension along with raised intraocular and intracerebral pressure.3

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