Tracheal intubation using a laryngoscope is considered to be the gold standard of airway management during administration of general anesthesia because of its several advantages including delivery of anesthetic gases and oxygen via positive pressure ventilation without inflationof stomach, minimal risk ofaspiration, access to tracheobronchial tree for pulmonary hygiene and drug administration (e.g., inhaledbronchodilators), improved surgical access to head andneck.1,2 Direct laryngoscopy and tracheal intubation during general anesthesia leads to sympathetic stimulation and release of plasma catecholamines concentration which manifests clinically as tachycardia, hypertension along with raised intraocular and intracerebral pressure.3 Normally these hemodynamic responses have its peak effect within 1 -2 minutes after intubation and are normalized within five minutes post intubation, but the response may be unpredictable in duration as it also depends upon co-morbid conditions of the individual patients. Sometimes the abrupt increase in heart rate and systolic blood pressure may lead to adverse effects in patients of cardiovascular and cerebrovascular diseases, compromising myocardial contractility and oxygen supply.4-6 Variety of pretreatments ranging from topical anesthesia of larynx to administration of several classes of drugs like nitroglycerine, B blockers and opioids have been made. Each technique has its own disadvantages, so many times multi modal therapy rather than single intervention has been in practice to attenuate this response.7