Objective - To compare the efficacy of derma roller versus TCA CROSS technique for the treatment of acne scars in tertiary care hospital. Methods – This was a hospital – based, non interventional, cross- sectional study carried out over a period of 3 months on 60 patients with post acne scarring. Group 1 patients underwent four sessions of dermaroller therapy four weeks apart. Group 2 were treated with four sessions of TCA CROSS technique four week apart. Results – Out of 60 patients in the study, 32 were male and 25 were females. Male patients had more severe acne vulgaris as compared to female (p=0.0001). Morphologically, majority of post acne scars were rolling in both the groups 75.86% in dermaroller group and 67.85% in TCA CROSS group. After four sessions of Dermaroller and TCA CROSS each, very good improvement was seen in 41.32 % patients in the dermaroller group and in 14.28% patients in tca group. Good improvement was seen in 51.72% in dermaroller group and 67.85% in tca group and no improvement was seen in 6.89 % in dermaroller group and 17.85 % in tca group. Side effects were mild and infrequent in both groups. Conclusion – Both treatments are equally effective and safe for the treatment of acne scars.