Background and Objectives: In the present day practice of Anesthesia, bupivacaine is the most commonly used drug for spinal anesthesia. To improve upon the quality of analgesia and prolong the duration of its action, many adjuvants have been tried. Intrathecal clonidine, an α2 adrenergic receptor agonist has potent central anti-nociceptive properties with analgesic effect at spinal level mediated by post synaptically situated adreno receptor in dorsal horn of spinal cord. Buprenorphine, an opioid, has analgesic effect when given in the sub arachnoid space by acting primarily at the µ receptor in the substanstia gelatinosa of the dorsal horn. It suppresses the excitatory neuropeptide release from C fibers. Low doses of clonidine and buprenorphine have shown effectiveness in prolonging the duration of action and improving the quality of analgesia during spinal anesthesia