Online ISSN: 2515-8260

Comparative study of analgesic efficacy, hemodynamic stability, and adverse effects of injection Buprenorphine versus Dexmedetomidine as adjuvant with 0.5% hyperbaric bupivacaine in patients undergoing moderate duration surgeries

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Santosh Gitte1 , Vivek A. Patange2 , Sangita Agale3

Abstract

Background: Intrathecal opioids are the gold standard for the treatment of postoperative pain with Buprenorphine adjudged as the most effective due its potent and prolonged effects. However, over the years it is losing popularity due to dose dependant side effects such as pruritus, nausea, vomiting and the most feared risk of delayed respiratory depression. Hence the search for an agent which can provide potent postoperative analgesia as comparable to morphine without its side effects still continues.

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