Sthoulya(Obesity) is the major and basic cause of lifestyle disorders like Diabetes mellitus,Hypertension, Coronary heart disease. Sthoulya(Obesity) is increasing at an alarming rate in developed industrialized countries which are undergoing rapid nutrition and lifestyle transition. Obesity is one of the most effective diseases which affect someone’s social, physical and mental status. In Ayurveda; Sthoulya (Obesity) is regarded as Medoroga, a disorder of MedaDhatu, which includes fat tissue and fat metabolism. According to Ayurveda;Sthoulya begins with an imbalance of Doshas (Vata, Pitta and Kapha), Agni (digestive fire), Malas (waste products) or an imbalance of Srotas (microcirculatory channels). This collection of imbalances then interferes with the formation of tissues or Dhatus and leads to a tissue imbalance that we experience as excess weight. Overweight and obesity are linked to more deaths worldwide than underweight. Overall, about 13% of the world adult population (15% of women and 11% of men) was obese in 2016. The worldwide prevalence of obesity nearly tripled between 1975 and 2016. Around 5-8.8% of school children are obese in India. And if the rates increase at a pace like this, 27 million Indian children will be obese by 2030. Now a day’s every person is running after life’s goal hence does not have time to think and act for healthy life and not able to follow the proper Dincharya, Ritucharya, Dietetics rules and regulations. Due to artificial living lifestyle, person suffers from so many disorders for themselves;Sthoulyais one of them. Keeping in the view of above concepts, research work entitled“Comparative Clinical Study ofrole of MustadiKwathGhanvati in Sthoulya (Obesity) by AntaparimarjanandMustadiChurna in BahiparimarjanChikista”is taken into consideration. The result of study showed that excessive intake of oily and fatty food, sedentary lifestyle, and psychological factor along with genetically predisposition play a major role in aetiopathogenesis of Sthoulya(obesity). Furthermore it was also found that MustadiKwathGhanvati effectively helps in reducing weight & BMI ratio. The effect of study shows that MustadiKwathGhanvati provided better relief as compare to MustadichurnaUdhavartana in the management of Sthoulya