AIM: The present study was carried out as an attempt to correlate and emphasize the salient approaches to the diagnosis and treatment of the various acute abdominal conditions. Material and methods: This study was a prospective observational study consisted of 50 patients with non‑traumatic acute abdomen presenting to the ED that were clinically diagnosed acute abdomen. Detailed history was taken followed by clinical examination and radiological investigations for all the patients. Comparative analysis of all investigations and clinical features were made and a provisional diagnosis was derived. Results: The results showed that mean age of the patient is 38± 13.6 years with M: F ratio of 1:3.5. Acute cholecystitis was the most common cause of acute abdomen, accounting for 36% of total cases followed by perforation peritonitis (24%) which included peptic perforation and intestinal perforation. The accuracies was recorded for clinical features, ultrasonography andXray for acute abdomen cases. Conclusion: We concluded that Plain X rays and ultrasonography can be used for diagnosing acute abdominal emergencies; they are the cheaper, non-invasive, quick, reliable and highly accurate modality in diagnosing the exact cause of pain and its origin in a patient presenting with an acute abdomen and thus helps the physician or surgeon to plan the timely management.