BACKGROUND: Our aim is to study the histological subtypes of gastric carcinoma and its association with H-Pylori. METHODS: Over 120 endoscopic gastric biopsies and 80 gastrectomy specimens received in our department during the period 1st January 2015 to 30 Nov 2016 were studied. RESULTS: The total numbers of 200 cases of gastric carcinoma were evaluated out of which 80 were gastrectomy specimens and 120 were from gastric endoscopic biopsies. When Lauren classification was used to classify histological type of tumor ,out of 200 cases maximum were intestinal type 105 cases (52.5%) followed by diffuse type 81 cases (40.5%). There were 14 (7%) cases of unclassifiable/mixed type in this study. It was observed that Males were predominantly affected by intestinal type( 80 cases, 40%) of gastric adenocarcinoma, followed by diffuse type (53cases,26.5%) whereas the reverse was seen in females as they were affected by diffuse type in (28 cases,14%) followed by intestinal (25 cases,12.5%). It was also observed that diffuse type was more frequent in women than non-diffuse .When WHO classification was used to classify histological pattern of gastric adenocarcinoma, the tubular type (42%) turned out to be most prevalent followed closely by( 40.5%)poorly cohesive (including signet ring cell carcinoma) & then by papillary adenocarcinoma (8.5%), mucinous adenocarcinoma 2% (MAC), mixed adeno-neuroendocrine (1%) and adenosquamous carcinoma (1%) in decreasing order. The SCC(Squamous cell carcinoma)& HEPATIOD variants were the least common variants (0.5%) each. The association of Helicobacter(H) pylori with histological intestinal type of adenocarcinoma was statistically insignificant (p >0.05).Majority of patients had score 0 for Human epidermal growth factor receptor2(HER2) (66.66%) while 16.66% of patients showed a score of 3+suggesting HER 2 positivity. A score of 2+ i.e., equivocal was seen in 13.33% of cases and 3.33% of cases were of score 1+