Background: Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn’s disease, is increasingly being reported from India and other Asian countries. Both forms of IBD are associated with prominent extra-intestinal manifestations and an increased incidence of gastrointestinal cancer; in addition, both begin relatively early in life and persist for long periods, leading to decreased quality of life indices and a greater than two fold increase in mortality rate. Methods: The present study was Hospital based study and was done in the Department of Pathology, Government Medical College, Srinagar to analyse the Clinical and Histopathological Profile of patients with Inflammatory Bowel Disease in Tertiary Care Hospital. This was a two year study extending from Ist Oct 2019 to 30 September 2021.The study included biopsies and resected specimen received from Department of Medical Gastroenterology and General Surgery of GMC Srinagar.