The aim of this study was to evaluate the clinico-pathological profile of colorectal cancer patients in our tertiary care hospital. Material and methods: This prospective as well as retrospective study was conducted in Gastroenterology division of Department of General Medicine at Ananta Institute of Medical Sciences & Research Center, Udaipur, Rajasthan, India. Total 174 patients presenting with colorectal cancer (CRC) from August 2019 to July 2022 were included in the study. Study tools were Study-questionnaire, investigations [routine blood tests, CEA, Colonoscopy, USG, CECT and MRI] and histopathological reports. Parameters studied were age, sex, site of lesion, clinical presentations and histopathology of the lesion.