Macrovascular complications of diabetes mellitus include cardiovascular diseases, cerebrovascular accidents and peripheral vascular disease. Macrovascular disease is a significant cause of mortality in diabetic patients. Diabetic individuals have a multitude of risk factors for atherogenesis and the odds of developing coronary artery disease and ischemic strokes are 2 to 4 times and 2 to 3 times more, respectively, than non-diabetic individuals. This is a prospective observational comparative study in which 60 patients with type 2 diabetes mellitus in the age group of 35-65 years were included and results are compared with 60 Normal Individuals. The study design was approved by the Ethical Committee of the institution. In NN group, 12(85.7%) patients were on OHA, 02(14.3%) patients on insulin. In NH group, 19(82.6%) patients were on OHA, 04(17.4%) patient was on insulin. In HH group, 16(69.6%) patients were on OHA, 7(30.4%) patients were on insulin. The distribution of BMI among all the three groups was equal. P value was 0.215 which shows that the groups were similar to each other in the distribution of BMI.