In Asian populations, Kiebsiella pneumoniae is the most frequent pathogen associated with cryptogenic PLA‘s. Diabetes mellitus is suggested to be an important risk factor, but the pathogenesis is still unclear. E. coli is the most common pathogen in Western countries, in both monomicrobial and polymicrobial isolates, followed by Streptococcus milleri. Anaerobes may also be cultured from PLA‘s and Bacteroides spp. are the most common isolated organism. After obtaining approval and clearance from the institutional ethics committee, the patients fulfilling the inclusion criteria will be enrolled for the study after obtaining informed consent. Case record form with follow up chart. All cases had undergone thorough history and detailed clinical examination at the time of admission. Total and differential leukocyte counts was measured with an auto-analyzer. In this study it is found that liver abscess presents with most common presentation as pain abdomen and fever. In this study it is found that fever, loose stools are presenting features of liver abscess in most of the individuals along with pain abdomen.