Abstract The main aim of this research is to conduct an updated review of the literature on guided endodontics based on the most recent scientific research to identify and describe the technique, its advantages, and its disadvantages. From 1 January 2000 to december 2022, a literature search was conducted using four electronic databases: PubMed, Scopus, Science Direct, and Web of Science. Out of 1088 results, 34 articles could be reviewed after duplicates were eliminated. Guided endodntics is a novel technique that is currently advancing. It is used in a variety of procedures, particularly in microsurgical endodontics, accessing and locating root canals in teeth with pulp canal obliteration, and removing glass fiber posts in endodontic retreatments. Additionally, it is unaffected by an operator's level of experience and requires less treatment time for the patients and is more precise and safer than conventional endodontics.