Abstract Introduction: Tuberculosis is a huge public health worry with high mortality rate. Usually presents with non- tender lumps in the neck region, malaise and weight loss. This study was undertaken to study the clinical and epidemiological profile of tubercular cervical adenitis. Objective: To study the clinical and epidemiological profile of tubercular cervical adenitis and to determine and assess the outcome of anti- tuberculous treatment (ATT) in these patients. Methods: A hospital based descriptive study was conducted among 35 subjects at a tertiary teaching hospital in Hyderabad for a period of one year. The collected data was analysed using SPSS version 21. Results: The mean age was 31.1±12.8 years consisting of 13 males and 22 females. The swelling was tender in only one subject, hard in 74.3% and firm in 25.7%. FNAC was done in 94.3% and biopsy was done in 11.4%. All the 35 subjects were started on anti- tubercular treatment category I. Relapse was seen in 3 subjects. On association anti tubercular treatment of tubercular cervical adenitis increased the cure rate (p<0.04) and the chances of relapse was reduced (p<0.001). Conclusion: High- cure rate and low relapse rate was observed with minimal adverse effects.