The article presents the results of the study of cases caused by the non-medical use of ketamine hydrochloride, which belongs to the phenylalkylamine group. There are increasing among minors the occurrence of serious crimes due to the use of ketamine hydrochloride for various non-medical purposes, severe poisoning and death in most cases as a result of their abuse. According to statistics, recently, the number of poisonings from ketamine hydrochloride, a representative of the phenylalkylamine group has been sharply increasing worldwide. There were studied information about the illegal consumption of ketamine hydrochloride is given in the literature, and the methods and techniques of the research conducted in connection with the study of cases of poisoning with them.