Background:A mysterious pneumonia case was first reported in Wuhan, China in December 2019. The World Health Organization (WHO) later named this pneumonia Coronavirus Disease (Covid-19) caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virus. The massive spread of Covid-19 increases the risk of co-infection with other pre-existing pathogens including malaria Case Report: A 32 years old woman was admitted to the hospital due to complaints of jaundice, fever, dyspneu and andominal pain. On further examination of the malaria smear, plasmodium falciparum was found in the form of trophozoites and gametocytes, the parasite count was 119,902 U/L and a nasopharyngeal PCR swab was positive for SARS CoV-2. The patient conditionimprove after administering artesunate and oseltamivir. Discussion: Several clinical manifestations are overlapping between Covid-19 and malaria, especially extrapulmonary manifestations of Covid-19 infection, including thrombocytopenia, elevated transaminase enzymes, increased bilirubin, and impaired kidney function. Management was carried out to deal with malaria and Covid-19 simultaneously and continuously.