Abstract. This article provides suggestions and comments on the development of new legislation based on new definitions, improvement of normative legal acts and their analysis related to the use of biological resources for scientific purposes and ensuring biological safety. It also analyzes the most important issues that contribute to the further development of the theory of environmental law in the field of protection and use of biological resources. On issues related to the use and protection of biological resources, analytical information on the establishment and effective functioning of scientific institutions, their legal status, biological threats and biological safety will be provided. It is argued that biological security is an important branch of national security. Natural ecosystems and their use, ie livestock, irrigated agriculture, forestry, fisheries, recreation, tourism and other sectors of the economy is directly related to biodiversity. Given the role of the environment, international regulation of the use of genetically modified organisms (GMOs) and their by-products is important. Biosafety alone is a pressing issue in the world. Documentation in this regard allows minimizing potential risks to the environment and human health. Finally, the legal use of biological resources for scientific purposes and the legal provision of biological safety provide a number of environmental legal recommendations related to the COVID-19 pandemic.