ABSTRACT: Bioactive peptides are chemical functional substances which are linked by covalent bond and are formed by amino acid residues. The essential requirement of food derived bioactive peptide increases day by day due its important property, for example high affinity, efficiency specificity which play vital role in human health by promoting digestive, endocrine, cardiovascular, immune system. They also known as future biological active regulators which help to reduce the chances of oxidation and microbial degradation in food stuff. The biological active substance having different considerable activities which includes antiproliferative, antioxidant, antimicrotubular, these activities are identified from the marine animal sources, specifically algae and cyanobacteria, which act as a secondary metabolite. Milk also contain rich amount of soluble and insoluble protein that is whey and casein protein. Alcalase potato protein hydrolysate (APPH) and germinated soya bean protein are bioceutical and play role in anti -obesity as well as anti-diabetes. The different presumed biological activities found in glutellin which carry at least 21 peptides with~53% of the nut storage protein. These activities are anti-hypertensives, antioxidants, immunomodulators, antimicrobial, anti-thrombotic, anti-cancer, hypocholesterolemic, anti-obesity and protease inhibitors that inhibits the cell cycle progression in cancer cells. These peptides have many advantages than the synthetic drugs. There is need to establish favourable condition to develop bioactive peptides for the human welfare in terms of treating many diseases as well as food beverages.