Background: Cholangiocarcinoma, including intra-and extrahepatic cholangiocarcinoma, is a rare but highly lethal cancer. Despite effort in finding the risk factors of cholangiocarcinoma, the causes of most cholangiocarcinoma remain unknown.There are considerable geographic and demographic variations in the incidence of cholangiocarcinoma. Although it comprises only 10-15% of hepatobiliary neoplasms, its incidence is increasing. There are several established risk factors for CC and few are modifiable which will help in reducing the incidence. Aims and Objectives: To study the Prevalence and risk factors of cholangiocarcinoma at GMC Budaun. Material and Methods: All types of cholangiocarcinoma cases above age of 40 years admitted to Department of Surgery, GMC Budaun U.P., were studied for risk factors over a period of two years. Results: An incidence of cholangiocarcinoma was 0.032% in present study. Peak incidence of cholangiocarcinoma was 4th to 6th decade of life with mean age of 61.92 years. out of 26 patients 13 patients (50%) were smoker and in those 13 patients 12 (92%) were smoking for more than 10 years and 13 patients (100%) were smoking more than 10 cigarettes or bidi per day. 18 patients were using chulha (69%) for cooking meals with coal as a primary fuel. Conclusion: In conclusion, we found associations with PSC, smoking and alcohol consumption; however, further studies are needed to establish the risk factors in our country Long term exposure to pesticides in patients, who are chronic smoker and exposed to smoke from chulha are at higher risk of developing CCA than others in this socioeconomic scenario.