INTRODUCTION:The human immunodeficiency virus (HIV) is grouped to the genus Lentivirus within the family of Retroviridae, subfamily Orthoretrovirinae .On the basis of genetic characteristics and differences in the viral antigens, HIV is classified into the types 1 and 2 (HIV-1, HIV-2) . Before 1996, few antiretroviral treatment options for HIV-1 infection existed. The clinical management of HIV-1 largely consisted of prophylaxis against common opportunistic pathogens and managing AIDS-related illnesses. AIM : To assess the knowledge and awareness of antiretroviral drugs in HIV patients among dental students. MATERIALS AND METHODS: A cross sectional questionnaire was designed and distributed to 100 dental students. Questionnaire includes email address, questions aboutART, objectives of ART, group of antiretroviral drugs and newer drug for treating HIV infection. Data was collected, statistically analysed and results were obtained. RESULTS: Among the study population, majority (90%) aware of antiretroviral therapy (ART) whereas 9% of the study population not sure about antiretroviral therapy and 1% of the study population not aware of antiretroviral therapy. CONCLUSION: The findings observed in our study showed that awareness and knowledge of antiretroviral drugs for HIV patients among dental students were high. But, dental students were not aware of recent drug approved for adult patient living with HIV who tried multiple medications and whose HIV infection cannot be successfully treated.