Online ISSN: 2515-8260

Association of oxidized LDL, Lipid profile with Psoariasis - A tertiary care center perspective

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Bibek Bhurer Yadav1 , Soni Ankita2 , SK Bansal3 , MPS Sawhney4 , NK Singh5 , Busi Karunanad6 , Shikhar Ganjoo7 & Kapil Hazarika8

Abstract

Background: Psoriasis is a common, genetically determined, inflammatory and proliferative dermatological disorder that affects skin, nails & joints characterized by keratinocyte hyperplasia leading to erythematous oval plaques with adherent silvery scales and has various systemic involvements. Psoriasis has been associated with an increased risk of atherosclerosis, including coronary artery disease (CAD) and stroke, for decades. Recent evidence suggests that oxidation (Ox) of LDL plays an important role in the pathogenesis of atherosclerosis and cardiovascular diseases. Our study therefore aims to assess ox-LDL and lipid profile in patients with psoriasis with an objective to observe and report any significant deviations in the same as compared to healthy controls.

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