Online ISSN: 2515-8260

Assessment of Ventricular Function in Children with Bronchial Asthma

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Dalia Soliman Abdullah 1 ,Eman Mahmoud EL- Moghazy2 , and HebaAbouZeid3

Abstract

Background:Bronchial asthma is a chronic inflammatory disease of airways in which many cells and cellular elements play a role particularly mast cells, eosinophils, T lymphocytes, macrophages, neutrophils and epithelial cells.Chronic bronchial asthma may cause pulmonary arterial hypertension which causes RV hypertrophy and dilatation as well as systolic and diastolic RV dysfunction. The level of right ventricular diastolic dysfunction depends on the degree of right ventricular hypertrophy and pulmonary vascular resistance. Aim of the study: The aim of this study wasto evaluatethe ventricular functions in patients with bronchial asthma using Traditional Echocardiography and tissue Doppler imaging. Patients and methods:This was a cross sectional study that included thirty-eight patients with bronchial asthma. All patients were subjected to full history taking, clinical examination and they underwent Echocardiography. Results:Tricuspid and mitral E wave velocities were significantly lower among cases. Tricuspid and mitral A wave Velocities were significantly higher among cases. No significant differencewas found regarding any of the measured cardiac dimensions. No significant statistical difference regarding fractional shortening was found.Right ventricular myocardial performance (MPI) was higher in case group when compared to control group with no significant statistical difference. Conclusion:Early and late biventricular diastolic dysfunction was detectable in children with bronchial asthma using conventionalDoppler echocardiography. The absolute value of right ventricular tissue Doppler-derived MPI was increased in cases of bronchial asthma compared with control subjects although the difference did not reach statistical significance.

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