failure (refHF) is decreasing, with a stabilization of mid-range ejection fraction heart failure (mrHF) prevalence and rise in number of patients with preserved ejection heart failure. The present study was conducted to assess relationship between serum uric acid and ejection fraction of the left ventricle. Materials & Methods: 48 patients of chronic heart failure of both gendersunderwent cardiac ultrasound. Measurement of planimetric ejection fractions and left atrial volume were taken. Patients were divided into 3 groups based on ejection fraction. Group I had EF >50%, group II between 40-49% and group III had <40%. 5 ml venous blood samples were taken, and measurements of biochemical parameters such as serum electrolytes (Na+ and K+), serum creatinine (SC), and a lipid panel and serum uric acid (SUA) were performed. SUA was measured. NT-proBNP levels were also measured for all patients.