Background: Generic drugs have an important place in health care because they are less expensive and mimic the original drug in terms of the active ingredients, dose, dosage form, and bioequivalence.The present study was conducted to assess patient perception about generic vs. branded medicine. Materials & Methods: 120 patients of both genders were provided with a questionnaire was designedwhich comprised of knowledge about difference between generic and branded medicines, attitude for buying generic medicines over branded medicines and practice of taking generic medicines.