Background: Iron deficiency has been related toimpaired cardiac function and altered myocardial structure in animal models. The present study was conducted to assess ferritin deficiency in heart failure cases. Materials & Methods: 58 patients of heart failure of both genders were included and parameters such as ferritin, serum iron, total iron binding capacity, transferrin and transferrin saturation(TSAT) were measured. Results: 58 patients were taken in which males were 38 and females were 20. Iron deficiency was seen in 12 males and 18 females and no iron deficiency was observed in 15 males and 13 females. The difference was non- significant (P>0.05). The mean hemoglobin in iron deficiency patients was 11.2 g/dl and those without iron deficiency was 13.6 g/dl. Iron level was 56.8 µg/L and 92.5 µg/L, MCV was 84.2 fl and 90.6 fl, TSAT was 14.1% and 29.7% and ferritin was 78.4 µg/L and 265.2 µg/L respectively.