Background: To evaluate the Bilateral Asymmetry in the Humerus of Human Skeletal Specimen. Materials & methods: A total of 100 sets of skeletons, both female and male, of different ages and geographical origins were enrolled. Weight of humerus bone was assessed on a weighing balance. Humerus length was determined by using an osteometric board. Mid-Shaft Circumference was assessed using a millimeter graph paper at the level of the apex of the deltoid V. All the dimensions were recorded in Microsoft excel sheet and were quantified. All the results were recorded and analysed using SPSS software. Results: Among the males, mean weight of left and right humerus was 118.3 grams and 117.2 grams. Mean length of left and right Humerus was 32.91 cm and 32.83 cm respectively.Mean mid-shaft circumference of left and right Humerus was 5.95 cm and 5.72 cm respectively. Among the females, mean weight of left and right humerus was 103.5 grams and 103.1 grams. Mean length of left and right Humerus was 31.12 cm and 30.99 cm respectively.Mean mid-shaft circumference of left and right Humerus was 5.62 cm and 5.49 cm respectively